Immune Cell Killing Assay
Cytotoxic immune cells can recognize and kill target cancer cells. Immune cell killing assays are a valuable tool for immuno-oncology research projects for in vitro assessment of these cells. With SIEVEWELL, the dynamic interactions of immune and cancer cells can be visualized.
The erythroleukemia K562 cell is known as a NK-cell sensitive target. Calcein AM-stained K562 cells were loaded into SIEVEWELL 50 μm, then KHYG-1 cells, NK leukemia cell line, were loaded by sedimentation. Time-lapse images were taken every 3 minutes.